Dendritic cells and vaccines
Ralph M. Steinman, MD
Since no abstract is available, the first paragraph is reprinted.
Immunology plays an important role in many clinical conditions. In some instances-such as infectious diseases and cancer-the goal is to improve the immune response to the pathogen or challenge; in other instances-such as transplantation, autoimmunity, and allergy-the goal is to reduce the specific immune response. Already, immunology is providing valuable therapies, mainly in the form of monoclonal antibodies. Anti-tumor necrosis factor (TNF) is being used to treat arthritis and other inflammatory diseases, and anti-CD20 is being used to treat B cell lymphoma. However, the T cell limb of the immune response also needs to be harnessed in a disease- or antigen-specific manner in medicine.
|
Baylor Intranet | 
Baylor Portal