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Institute of Metabolic Disease at Baylor Research Institute
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Vitamin B6 (pyridoxal phosphate)
Vitamin B6 or pyridoxal phosphate plays a vital role in the function of numerous enzymes. Some essential functions of vitamin B6 include: synthesis of neurotransmitters, processing the essential fatty acid linoleic acid, assisting in the release of glycogen for energy from the liver, formation of niacin, and helping the body to manufacture and convert amino acids and metabolize proteins.
Adequate amounts of vitamin B6 are also required to keep blood total homocysteine levels low. Low intake of vitamin B6 may lead to depression, cognitive impairment, cardiovascular disease and impaired immune function.
Department: Neuropharmacology
Methodology: HPLC with fluorescence detection
Sample:
. Plasma - 0.25mL heparinized plasma
. Serum - 0.25 mL
. Cerebrospinal fluid - 0.25 mL
Handling:
. Plasma and Serum -spin down the sample within 1 hour of collection.
. Cerebrospinal Fluid - freeze CSF immediately and store at -80°C until transport.
Shipping:
. Plasma and Serum - Ship sample overnight with 3-4 lbs of dry ice using a guaranteed overnight courier.
. CSF - Ship sample Monday through Wednesday only. Ship sample overnight with 3-4 lbs of dry ice using a guaranteed overnight courier.
Special Notes: This research test must be coordinated through the Neuropharmacology Laboratory Director. Most research tests are performed on a batch basis; the laboratory will not perform single sample testing. Contact the Neuropharmacology Laboratory Director for more information.
Turnaround Time and Test Cost: Contact the Neuropharmacology Laboratory Director.
Related tests: Homocysteine-Research, Methyltetrahydrofolate, Folate (total), Vitamin B12
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