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Institute of Metabolic Disease at Baylor Research Institute
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S-adenosylmethionine (SAMe)
S-adenosylmethionine (SAMe) is the major methyl donor in numerous methylation reactions such as proteins, DNA, phospholipids and neurotransmitters. Decreased levels of SAMe commonly occur in the presence of folate and cobalamin (vitamin B12) deficiency. Low SAMe levels have been associated with depression, dementia, vacuolar myelopathy and liver disease.
Department: Neuropharmacology
Methodology: HPLC and UV detection
Sample:
• Plasma – 0.25mL heparinized plasma
• Cerebrospinal fluid – 0.25 mL
• Tissue – 100 mg
Handling:
• Plasma – spin down the sample within 1 hour of collection.
• Cerebrospinal fluid and Tissue- freeze immediately and store at -80°C until transport.
Shipping:
All sample types - Ship sample overnight with 3-4 lbs of dry ice using a guaranteed overnight courier.
Special Notes: Contact the Neuropharmacology Laboratory Director prior to submitting a sample.
Turnaround Time and Test Cost: Contact the Neuropharmacology Laboratory Director
Related tests: Homocysteine, Folate (total),Vitamin B12, Vitamin B6 |
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