Monitoring Blood Genome Activity during Pregnancy

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	Harnessing Human DC Subsets for Improved Mucosal Vaccines
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	Supplement #3 to ‘Harnessing Human DC Subsets for Improved Mucosal Vaccines’
	Immunotherapeutic HPV Cancer Vaccines that Target Langerhans Cells
	Improving the Efficacy of Dendritic Cell Vaccines
	JC Virus and Tumor Formation in the Human Colon
	Monitoring Blood Genome Activity during Pregnancy
	Novel Dendritic Cell-Based HIV Vaccines
	Rural Hospital Collaborative for Excellence Using IT
	Towards an HCV Vaccine
	Transcriptional Signatures for Diagnosis of Different Spectra of Mycobacterium tuberculosis Infection and Characterization of the Immune Response during Latency or Active Disease
	Use of Microarrays to Understand Systemic Arthritis
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PI: Damien Chaussabel, PhD
Funding Organization: The Discovery Foundation
Project Start: November 21, 2008
Project End: November 21, 2011

Abstract:
The goal of this project is to improve heath monitoring and early disease detection in women during pregnancy. Specifically this effort will aim at:
- Establishing the systematic collection of blood samples in women followed throughout their pregnancy at BUMC and creation of a repository for genomic research.
- Identifying baseline changes in blood genome activity occurring during the normal course of pregnancy.
- Identifying changes in blood genomic activity associated with complications that occur during pregnancy and evaluating the potential use of genome-wide blood screens for health monitoring and early detection of complications during pregnancy.