Grant number: RP150638
Principal Investigator: Arianne L. Theiss
Funding Organization: Cancer Prevention Research Institute of Texas (CPRIT)
Project Start: 07/01/2015
Project End: 06/30/2017
The goals of this proposal are to determine whether elevated levels of D-2-HG during colitis drive progression to colorectal cancer and to define the role and therapeutic potential of targeting EglN1/Hif1a/D-2-HGDH pathway in colitis-associated cancer.